Palladium(II)-catalysed regioselective synthesis of 3,4-disubstituted quinolines and 2,3,5-trisubstituted pyrroles from alkenes via anti-Markovnikov selectivity.

نویسندگان

  • Gopal Chandru Senadi
  • Wan-Ping Hu
  • Amol Milind Garkhedkar
  • Siva Senthil Kumar Boominathan
  • Jeh-Jeng Wang
چکیده

A novel strategy has been identified for the regioselective synthesis of 3,4-disubstituted quinolines and 2,3,5-trisubstituted pyrroles from simple alkenes via anti-Markovnikov selectivity under palladium catalysis. The salient features are synthesis of two different heterocycles, readily available starting materials, broad substrate scope, moderate to good yields and use of molecular oxygen as a terminal oxidant.

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عنوان ژورنال:
  • Chemical communications

دوره 51 72  شماره 

صفحات  -

تاریخ انتشار 2015